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Wednesday, April 12, 2006
  How to print a beating heart
NewScientist.com
This week's top stories from the web's No.1 science and technology news service
12 April 2006
Welcome to the New Scientist newsletter, which this week reveals a technique to "print" bespoke living tissues, the cocaine hidden in clear view, and the aerodynamic insights from an eagle in flight...
Edinburgh Science Triangle
Will Knight
Will Knight, Senior Online Reporter
Artery Prints

Sitting in a culture dish, a layer of chicken heart cells beats in synchrony. But this muscle layer was not sliced from an intact heart, nor even grown laboriously in the lab. Instead, it was "printed", using a technology that could be the future of tissue engineering. Droplets of "bio-ink" - clumps of living cells a few hundred micrometres in diameter - flow together and fuse when squirted close to each other. They can be made to form layers, rings and tubes - which could serve as blood vessels - depending on how they are deposited. Bioprinting could develop into a fast and cheap way to engineer a variety of tissue types...MORE

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Gangs turn cocaine into clear plastic products Premium
Smugglers may be trying to incorporate cocaine into host of innocent-looking plastic consumer products, such as fish tanks and DVD cases

All the pleasures of alcohol, with no downsides
There is no reason why a cocktail of drugs to mimic the good effects of a few drinks cannot be made right now - it's an idea worth toasting

Are prions the real cause of BSE and vCJD? Premium
Abnormal prions - misshapen versions of normal brain proteins - may not be infectious agents, but a consequence of "prion diseases"

Tenth planet as bright as fresh snow
It is only slightly larger than Pluto, new images prove - but this means the distant world must be incredibly reflective, suggesting it is constantly being resurfaced

Mamma mia! Eurovision voting scandal uncovered
Mathematical analysis has revealed what everyone watching it already knew - conspiracies are afoot in the Eurovision song contest

Eagle-cam provides aerodynamic insights Video available
Cameras and sensors mounted on a free-flying eagle may help the shape-shifting aircraft of the future to perform dare-devil aerobatics

LAST WORD
 
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Fast language learners boast more white matter
The research is part of a growing understanding of how scans of brain shape and structure can give information about people's abilities

Invention: Wing-sprouting drone
This week's patents feature the drone that saves launch-fuel by being fired from a gun before inflating its wings, and transistors made of pure diamond

Genome-in-a-day promised as DNA is put through hoops Premium
It took a decade of hard slog to produce the first, momentous, human genome readout - but a new device may soon do the job in just 24 hours

Europe's Venus Express pulls into orbit
The first European spacecraft to visit Venus settles safely into orbit around Earth's "evil twin", poised to peel away its hothouse mysteries

Will replanting coasts protect against tsunamis? Premium
Some experts say fewer lives would have been lost in the 2004 tsunami, had the coasts been protected by dense coastal forests - but is it true?

Hybrid comet-asteroid in mysterious break-up
New images reveal something substantial has broken off an icy 50-kilometre object beyond the orbit of Saturn - it could have blown up or been hit

AND FINALLY ...
This week's Feedback column considers the radio-blocking power of tin hats, the perils of letting environmentalists make SUV commercials, and the mystery of "Lubricated Fair-Clips"...MORE

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Climate change: The great Atlantic shutdown Premium
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  MedlinePlus Health Information

(admin@honestmed.com) thought you would be interested in the following page from MedlinePlus�, the National Library of Medicine's consumer health web site:

Better health care doesn't erase racial gap

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_32033.html (*this news item will not be available after 05/07/2006)

Reuters Health Information 

Friday, April 7, 2006

NEW YORK (Reuters Health) - Efforts to improve health care quality can help reduce some -- but not all -- of the inequalities in medical care provided to black patients compared with whites, a new study shows.

Four years after launching a program to improve the quality of diabetes care, a large Boston-based physician group found that racial disparities in cholesterol screening were reduced, but blacks remained less likely than whites to be taking statins to get their LDL ("bad") cholesterol down, or to have their blood sugar under long-term control.

"While improving quality in general does result in reduction of disparities, what we found was that the more important measures of quality, which were the outcomes ... those things tended to have more persistent disparities," Dr. Thomas D. Sequist of Harvard Medical School in Boston, the study's lead author, told Reuters Health.

Sequist and his colleagues looked at 7,088 patients with diabetes -- 28 percent of whom were black -- who received care at Harvard Vanguard Medical Associates, to investigate the effect of quality improvement efforts on ethnic disparities in care. The initiative included patient outreach and electronic reminders sent to physicians.

As they report in the Archives of Internal Medicine, the team found that from 1997 to 2001, the percentage of patients who had their LDL cholesterol checked every year rose from 39 percent to 64 percent, while the disparity between blacks and whites fell from 14 percent to 4 percent.

During that same time period, the percentage of diabetic patients with their LDL cholesterol under effective control rose from 15 percent to 43 percent, with the racial disparity falling from 9 percent to 6 percent.

While the percent of patients taking cholesterol-lowering statins rose from 20 percent to 37 percent, there was no change in the disparity between blacks and whites taking the drugs, the researchers found.

Many factors could be at work here, Sequist noted. Physicians may be less likely to prescribe the drugs to black patients, or black patients could be less likely to fill the prescriptions, for example.

The percentage of patients with their blood sugar under long-term control remained at 31 percent throughout the study period. Racial disparities did not budge for this measurement; 24 percent of black patients had their blood sugar under long-term control, compared to 34 percent of whites.

Sequist and his colleagues point out that blood glucose control is a much more complex issue than lowering cholesterol, given that it may require changes in diet, exercise, and multiple medications.

It likely will be necessary for physicians to develop focused efforts to effectively address differences in care between blacks and whites in their own practices, Sequist told Reuters Health.

"A lot of health care disparities or the underlying reasons driving health care disparities do occur in a physician's office," he said.

SOURCE: Archives of Internal Medicine, March 27, 2006.



Copyright © 2006 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.


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Date last updated: 10 April 2006

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  MedlinePlus Health Information

(admin@honestmed.com) thought you would be interested in the following page from MedlinePlus�, the National Library of Medicine's consumer health web site:

Brand-Name Drug Prices Still Outpace Inflation

Generic drug costs down a bit, AARP survey finds

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_32133.html (*this news item will not be available after 05/10/2006)

Healthday 

HealthDay

Monday, April 10, 2006

MONDAY, April 10 (HealthDay News) -- There's a bit of good news in the latest AARP report that prescription drug prices continue to outpace the rate of inflation.

The rate of increase for a sample of 193 brand-name drugs was 6 percent in 2005, higher than the 3.4 percent inflation rate that year, but "that was a little more reasonable than in previous years," said John Rother, policy director at AARP.

And the average price of the 75 generic drugs monitored by AARP actually dropped, if only by 0.8 percent, in 2005, the report said.

"One bottom line for consumers is that the value of generic drugs is going up, so they can save even more money by switching to generics," Rother said.

That decrease in generics was due entirely to a drop in the price of 100 milligram tablets of the generic version of the antibiotic ciprofloxacin, down more than 38 percent in 2005. There were price increases for six generic drugs, while the prices of the other 68 covered in the report did not change, according to the report.

By contrast, the price increases for the 187 brand-name drugs used by older people for chronic conditions, such as high blood pressure, arthritis pain and cardiovascular disease, meant that the average annual cost per prescription was $47.43 higher in 2005, slightly better than the $51.82 increase in 2004, the report said.

Over the six years that AARP has been issuing its Rx Watchdog review, the average annual cost of therapy with brand-name products used to treat chronic conditions increased $297. But, typical older Americans regularly take four drugs, so their annual cost of therapy rose almost $1,200 from 1999 through 2005, the report said.

Looking at the 24 most widely used brand-name drugs, AARP found the highest price increase, 11.1 percent, was for Toprol XL 50-milligram tablets, a beta blocker marketed by AstraZeneca. The lowest increase among these best sellers, 2.9 percent, was for Plavix 75-milligram tablets, a clot-preventing drug marketed by Bristol-Meyers Squibb.

A prediction of higher prices to come was made by Sharon Treat, executive director of the National Legislative Association on Prescription Drug Prices. She said her pessimism was based on the terms of the new Medicare prescription drug program, which took effect at the start of this year.

The program, Medicare Plan D, requires participants to enroll with one of many private insurance companies, the terms of whose offers differ widely. "And the incentives are completely wrong," Treat said. "It makes no sense to have multiple programs, and there is no provision for negotiating prices with the companies. Anyone who looked at the law as it was being passed knew that it was wrong, and now what we predicted is happening."

Rother's appraisal was more cautious. The new Medicare program went into effect after the period covered by the latest AARP report, he noted, adding, "I don't want to speculate on what might happen. I don't think we can say yet."

Pharmaceutical companies "made a lot of pledges" about holding prices down, Rother said. If that does not happen, "it would invite more legislation by Congress," he said.

But the trend over the last six years has been for drug price increases to be higher than the general rate of inflation, Rother said, noting the average price increase of 40 percent, compared to inflation at 17 percent.

AARP releases its Rx Watchdog report periodically, tracking changes in drug pricing for its 35 million members aged 50 and older. The group bases its figures on changes in manufacturers' list prices for wholesalers.



HealthDay

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Date last updated: 11 April 2006

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